Study of Antimicrobial Susceptibility Test For Moraxella Catarrhalis in Hospitalized Patients of Respiratory Tract Infection

Abstract

Moraxella catarrhalis, a gram-negative diplococcui, an opportunistic pathogen that infects the human respiratory system. In th present study 20 isolates were collected from 405 individual clinical samples. Based on the sample source, the common sources of M. catarrhalis isolates were sputum 10 (50%), followed by throat swabs 8 (40%) and bronchial wash 2 (10%). Based on the culture morphology ("Hockey puck" sign), biochemical characteristics and with the API-NH, out of 354 (87.5%) positive bacterial growths, 20 (5%) isolates were identified as M. catarrhalis. In relation to biofilm development, the present study revealed that 5% of isolates were weak biofilm formers and 95% non-biofilm in formers in qualitative method (tube method). According to CLSI, The most effective antibiotics against M. catarrhalis were Amoxicillin-clavulanate and Trimethoprim-sulfamethoxazole the resistance rate was 2 (10%) and 1 (5%) respectively. The aim of the study is to investigate antibiotic resistance in M. catarrhalis in hospitalized respiratory tract infection patients.