Synthesis and characterization of Mn(II),Co(II), Ni(II),Cu(II) ,Ca(II) complexes with the ligand derived from indomethacin

Abstract

The 2-(1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl)-N'-(4-methylbenzylidene)acetohydrazide ( (IB) was synthesized through the condensation of hydrazide derived from indomethacin with 4-methyl benzaldehyde. Additionally, the complexes obtained from the ligand were characterized by infrared, UV-visible, ¹H, ¹³C NMR spectroscopy, elemental analysis, atomic absorption, molar conductance, and magnetic susceptibility. Measurements have shown that the ligand behaves as a bidentated ligand and is coordinated to the central metal ion through the oxygen atom for the carbonyl group and the nitrogen atom for the azomethine group. The structure of the ligand and complexes was confirmed. With the exception of the copper complex, which has an octahedral geometry, all of the complexes have adopted a tetrahedral geometry.